- We fabricated physiologically relevant microscale structures (e.g., cell-laden, three-dimensional, controlled actuation) by combining microfluidics, 3D printing, and bioprinting.
- Such structures will serve as a platform for drug development and fundamental biomedical studies.
- We developed easy-to-operate and low-cost methods to fabricate microfluidic devices, including toner printing, cutting/pasting, and 3D printing.
- We aim to apply low-cost fluidic devices for point-of-care diagnostics and in-house diagnostics to improve accessibility to healthcare.
- We aim to develop skin- and organ-adhesive sensors and actuators that can be operated wirelessly using flexible materials and conductive materials.
- The developed devices are applicable for real-time monitoring of biological surfaces, triggered drug release, and other biomedical applications.
- We developed unique methods of direct ink writing 3D printing (i.e., liquid 3D printing) based on the fluid properties of printing inks and surrounding fluids.
- Liquid-in-liquid printing enabled 3D printing of plastics and hydrogels. We aim to apply this technology for bioprinting.
- 3D food printing achieved fabrication of esthetically pleasing food and should be applicable for the personalization of foods (such as nutrition and texture).
Liquid-in-liquid 3D printing: We investigate the use of surrounding fluids for the fabrication of liquid polymer inks printed directly in other liquids. The surrounding liquids provide unique chemical and physical environments to facilitate the solidification of the printed ink.
- https://pubs.rsc.org/en/content/articlelanding/2019/mh/c9mh00730j#!divAbstract
- https://pubs.acs.org/doi/abs/10.1021/acsapm.0c01208
DIW 3D printing for microfluidic devices: We explore the use of direct printing of silicone and other flexible resins to fabricate devices on unique substrates to achieve unique functions of the devices.
- https://www.sciencedirect.com/science/article/abs/pii/S0925400519307981
- https://pubs.acs.org/doi/abs/10.1021/acsami.9b17567
Sacrificial printing and bioprinting: We investigate the use of (1) photopolymerizing resin and (2) sacrificial resin (resin that dissolves in hydrogels) to create cell-laden structures with vasculature-mimicking structures.
- https://onlinelibrary.wiley.com/doi/abs/10.1002/mame.201700484
- https://www.mdpi.com/2072-666X/9/10/523
3D food printing: We investigate the use of extrusion-based food printers to achieve 3D modeling of food to achieve the control over the function of the food (nutrition, texture and human response).